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Furthermore, the study NCT01303796, a Phase III clinical trial involving 482 AML patients, evaluated the efficacy of DAC (20 mg/m 2 once daily for 5 consecutive days every 8 weeks) + sapacitabine (300 mg twice daily on 3 consecutive days per week for 2 weeks every 8 weeks), an oral nucleoside analog

Financial disclosure The authors have the following to disclose: support provided by the Ministry of Health and Welfare (HI21C0694, Development of treatment for intractable skin diseases using low-molecular compounds with enhanced Wnt/beta-catenin), Republic of Korea

For example, alpha lipoic acid has shown promise in reducing oxidative stress markers and improving iron levels in -thalassemia major patients (84)

These cells were cultured in RPMI medium (21875-034, Gibco) supplemented with 10% FBS, 1% P/S, and 2 mM L-Glutamine